Yes definitely. What is your MIDI source and, more importantly, what kinds of messages is it sending?
In theory, the knob that you are working with should be able to respond to Program Change messages. On the other hand, if you want an increase or decrease PC message, that's another story.
Please create a new (related) question and let me know what's up, and then I can respond there.
Thanks and I'm glad we got this first question resolved.